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Laboratorio di ricerca

Lab. nameApplied Microbiology Laboratory and Microbial Genetic Laboratory 
Principal Investigator Moreno Bondi 
ComponentsMoreno Bondi  (Principal Investigator )
Carla Sabia   (Responsabile )
Patrizia Messi  (Responsabile )
Ramona Iseppi  (Assegnista )
Simona de Niederhausern  (Collaboratore )
DescriptionStudy of bacteriocin-producers (Lactic Acid Bacteria) and of their bacteriocins to be used as natural preservatives to improve quality and safety in food field. Study of antibacterial activity of plastic materials added with antimicrobial compounds (silver, essential oils, chitosan, bacteriocins, ecc.) to be used for active food packaging production. Study of biological characteristics (toxins, haemolysins, bacteriocins) influencing the virulence and responsible of selective pressure in microorganisms isolated from food, clinical and environmental samples; evaluation of survival of pathogens (Legionella pneumophila) and opportunistic bacteria (Aeromonas hydrophila, Pseudomonas spp.) and their interaction in different ecosystems and in the biofilm production. Evaluation of the chemo-antibiotic resistance in bacteria of clinical, environmental, food and animal origin. Identification and characterization of genetic determinants encoding for antibiotic-resistance, antibacterial activity and virulence factors through microbial recombination mechanisms and molecular researches.  
Addressvia Giuseppe Campi, 287 - 41125 Modena 
Keywordsbacteriocins, antibiotic-resistence, food-packaging, virulence-factors, biofilm  
ERC Sectors 
Instrumentation 
Research Lines Drug discovery, analysis, delivery and molecular engineering platforms

Plant, animal and microbial research for functional and sustainable food

Methodologies Bacterial cultures, studies of virulence factors and microbial competitions in bacteria of environmental, food and clinical source, challenge test, genetic recombination studies, study of plasmids by PCR, deferred antagonism and agar well diffusion for the bacteriocins evaluation, determination of minimal inhibitory concentration (MIC) of antimicrobial compounds, biofilm studies by optical/electronic microscopy