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Lab. nameBiochemistry and Glycobiology Lab 
Principal Investigator Nicola Volpi 
ComponentsNicola Volpi  (Principal Investigator )
francesca Maccari  (Ricercatore )
Fabio Galeotti  (Assegnista )
Veronica Mantovani  (Assegnista )
Federica Capitani  (Assegnista )
DescriptionGlycobiology and Glycomics. Structure and function of glycoconjugates, proteoglycans and complex polysaccharides. Biocompatible materials (biomaterials). Drugs SYSADOA (slow acting drugs). Study of the structure and function of complex polysaccharides and their degradation products in biological fluids, tissues and cells. Structural and functional characterization of complex polysaccharides (glycosaminoglycans) in invertebrates. Production and purification of acidic polysaccharides from bacteria by fermentation processes. Biotechnological modifications of natural polysaccharides complexes for therapeutic use. Study of the structure and function of complex oligosaccharides in biological fluids, tissues and cells. Study of the structure and function of glycoproteins in biological fluids, tissues and cells. Intolerances to food proteins in humans. Structural characterization of polyphenols and phenolic acids in active ingredients for pharmaceutical use and characterization of their antioxidant properties. Characterization of fatty acids in various simple and complex food, biological, pharmaceutical and nutraceutical matrices. Separation in HPLC, capillary electrophoresis, gas chromatography, horizontal and vertical electrophoresis of active biomolecules in various food, biological, pharmaceutical and nutraceutical matrices. 
Addressvia Giuseppe Campi, 287 - 41125 Modena 
KeywordsGlycobiology, Glycomics, Glycoconjugates, glycoproteins, polysaccharides, biocompatible materials (biomaterials), Drugs SYSADOA (slow acting drugs), Fatty Acids 
ERC Sectors LS1_2 General biochemistry and metabolism LS2_5 Glycomics  
InstrumentationBasic instrumentation for analytical and preparative Biochemistry laboratory. HPLC equipped with ternary gradient, post column derivatization, UV/VIS and fluorescence detectors. HPLC equipped with ternary gradient, UV/VIS and differential refractive index detectors. Electrospray Ionization Mass, off-line and on-line HPLC. Capillary electrophoresis equipped with detector UV/VIS. Capillary electrophoresis equipped with LIF detector. Gas chromatograph equipped with FID detector. LPLC equipped with gradient, UV and osmolarity detectors. Freeze dryers. Electrophoretic cells for SDS-PAGE, horizontal agarose-gel, agarose submarine. Apparatus for electrophoresis of oligosaccharides (FACE). Apparatus for the transfer from SDS-PAGE and western blot. Plate reader at variable wavelength. UV/VIS spectrophotometer. 
Research Lines Translational Medicine

Methodologies HPLC equipped with ternary gradient, post column derivatization, UV/VIS and fluorescence detectors. HPLC equipped with ternary gradient, UV/VIS and differential refractive index detectors. Electrospray Ionization Mass, off-line and on-line HPLC. Capillary electrophoresis equipped with detector UV/VIS. Capillary electrophoresis equipped with LIF detector. Gas chromatograph equipped with FID detector. LPLC equipped with gradient, UV and osmolarity detectors. Freeze dryers. Electrophoretic cells for SDS-PAGE, horizontal agarose-gel, agarose submarine. Apparatus for electrophoresis of oligosaccharides (FACE). Apparatus for the transfer from SDS-PAGE and western blot. Plate reader at variable wavelength. UV/VIS spectrophotometer.