Ti trovi qui: Home » Ricerca » Laboratorio di ricerca

Laboratorio di ricerca

Lab. namePharmacology and Toxicology 
Principal Investigator Lorenzo Corsi 
ComponentsLorenzo Corsi  (Principal Investigator )
Descriptiona) Study of new drugs and/or phtycomplexes acting as as potential anticancer This research aims to evaluate the anti-tumor potential of new compounds by identifying the molecular determinants acting on cytoskeleton organisation and cell division. b) Study of biochemical pathways involved in degenerative processes: new targets for anti-cancer compounds and/or preventing neurodegeneration: The purpose of this research is devoted to the study of new pathways involved in the process of degeneration (ie TSPO recepor complex; KIF 11, Rho A; etc) as a possible pharmacological target in cancer treatment or neurodegenerative disorders. c) Nanotoxicology: Evaluation of the potential carcinogenic and autoimmune activity of metal nanoparticles: in vitro studies. d) Toxicological evaluation of food supplements.  
Addressvia Giuseppe Campi, 287 - 41125 Modena 
KeywordsCancer, Nanoparticles, apoptosis, Cytotoxicity 
ERC Sectors LS4_6 Cancer and its biological basis LS5_2 Molecular and cellular neuroscience LS7_3 Pharmacology, pharmacogenomics, drug discovery and design, drug therapy LS7_5 Toxicology  
InstrumentationElisa spettrofotometer; Fluorometer; AFM 
Research Lines Translational Medicine

Methodologies Cell culture; molecular biology; (immunblotting; immunofluerscence, siRNA ecc); in vitro cell biology assay (apoptosis, BrdU, ,ROS, two stage trnasf. assay ecc)