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Gruppo di ricerca

Lab. nameLaboratory of genome editing and gene transfer  
Principal Investigator Alessandra Recchia 
ComponentsAlessandra Recchia  (Principal Investigator )
Daniela Benati   (Collaboratore )
Eleonora Cattin  (Collaboratore )
Tommaso Ferrari  (Collaboratore )
DescriptionMain activities are: development of genome editing approaches to correct genetic defects using viral vectors (AAV, adenovirus and lentivirus) and non viral vectors. Molecular and genomic analysis to assess the editing and the genotoxicity. 
Addressvia Glauco Gottardi, 100 - 41125 Modena 
Keywordsgenome editing; genetic defects; viral and non viral vectors 
ERC Sectors LS2_2 Gene editing LS2_14 Genetic diseases LS7_2 Medical technologies and tools (including genetic tools and biomarkers) for prevention, diagnosis, monitoring and treatment of diseases LS9_2 Applied genetics, gene editing and transgenic organisms  
Instrumentationconfocal microscopy (LSM 510 META, Zeiss) and related image acquisition apparatus; laser micro-dissector (PALM MICROBEAM, Zeiss); FACS (BD FACS CANTO II, BD); conventional PCR termocycler and RT-CR system (7900HT Fast Real Time PCR System, Apply Biosystems); Luminometer and ELISA reader (Glomax 96 Microplate Luminometer, Promega); NucleofectorTM device (Amaxa); Nanodrop® ND-1000 UV-Vis Spectrophotometer; tissue culture BL2 room equipped with: 3 laminar flow hoods, 2 CO2 incubators, 1 refrigerated supercentrifuge, 2 microscopes.  
Research Lines Translational Medicine

Methodologies Genome editing with engineered nucleases e.g. ZFN , TALEN and CRISPR/Cas9. Development and production of AAV , Adenoviral and lentiviral vectors for research uses 
Web Site @Recchia_Lab