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Gruppo di ricerca

Lab. namePHYTO and MORE  
Principal Investigator Stefania Benvenuti 
ComponentsStefania Benvenuti  (Principal Investigator )
Bendetta Catellani  (Membro )
Enrico Rossi  (Dottorando )
DescriptionMedicinal plants are today still the primary form of health care for the developing countries and also widely used as supplement or substitute to conventional drugs in the developed ones. These products require a pharmaceutical level of assurance for efficacy and safety in their use. Multiple constituents, working “synergistically”, are usually responsible for their therapeutic effects. Consequently, it is necessary to define all the constituents of plant extracts and nutraceuticals to understand the bioactivity and possible adverse effects of active compounds, and to enhance product quality control. High-performance liquid chromatography (HPLC) and gas chromatography (GC), often hyphenated with mass spectrometry (MS), are highly recommended methodologies and widely applied in the ambit of natural product analysis. The expertise of the “PHYTO AND MORE” laboratory is specific for this ambit of research and the studies which have been carried out in recent years were developed thanks to national and international research collaboration. 
Addressvia Giuseppe Campi, 103 - 41125 Modena 
Keywordsphytochemical analysis, chromatography, extraction, natural products, essential oils 
ERC Sectors LS2_9 Metabolomics LS6_6 Infectious diseases LS6_9 Antimicrobials, antimicrobial resistance LS9_10 Veterinary and applied animal sciences LS9_11 Biomass production and utilisation, biofuels PE4_9 Method development in chemistry PE5_18 Medicinal chemistry  
InstrumentationHPLC-UV, HPLC-DAD, HPLC-ESI-MSn (CIGS), HPLC-ESI-MS/MS (CIGS), GC-FID, GC-MS (LADAC), TLC, spectrophotometer 
Research Lines Agrifood and Environment

Translational Medicine

Methodologies Extraction and purification of bioactive compounds from plants; metabolite profiling/fingerprinting of natural products by means of advanced analytical techniques; method development and validation for the extraction and analysis of plant secondary metabolites; evaluation of the biological activity of plant extracts and isolated compounds (in collaboration with other research groups).