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Laboratorio di ricerca

Lab. nameBioinorganic Chemistry and Bioelectrochemistry Lab 
Principal Investigator Marco Sola 
ComponentsMarco Sola  (Principal Investigator )
DescriptionThe main research interest in our lab is the investigation of metal-containing, electron transfer (ET) proteins and enzymes involved in deseases. The aim is twofold: from a fundamental point of view, we are interested in unveiling how the protein structure, dynamics and environmental conditions affect the ET and the catalytic functionality. In parallel, our investigation is devoted to the design of bio(in)organic interfaces, based on the adsorption of metalloproteins on metal electrodes, for biosensing and biocatalysis. This approach makes the application of electrochemical methods also a very attractive strategy for the construction of reagent-less platforms for high-throughput screening of new drug candidates for cancer therapies. 
Addressvia Giuseppe Campi, 287 - 41125 Modena 
KeywordsMetalloproteins, Electrochemistry, Nanobiotechnology, Surface Scienc, Sensing 
ERC Sectors 
InstrumentationPotentiostat/Galvanostats and Uv-Vis spectrophotometer Orbital Shaker Incubator Refrigerators Thermocycler FPLC(Fast pressure Liquid Chromatography) Microcentrifuge Ultracentrifuge  
Research Lines Translational Medicine

Methodologies Surface Chemistry, Molecular Dynamics and QM/MM calculations, UV-vis, MCD, SERRS and Fluorescence Spectroscopy, Electrochemistry, Surface Chemistry Cloning, expression, purification of recombinant proteins