Laboratorio di ricerca
| Lab. name | Nutritional Biochemistry |
|---|---|
| Principal Investigator | Angela Conte |
| Components | Angela Conte (Principal Investigator
)
Davide Tagliazucchi (Collaboratore ) |
| Description | Research activities in the Nutritional Biochemistry lab: • Determination of peptide profiles during physiological digestion of milk and vegetable proteins. Fractionation, identification and characterization of antihypertensive, antioxidant and anti-cancer peptides in protein digests. • Determination and characterization of cell-envelope proteases of Lactobacillus casei and Lactobacillus rhamnosus (in collaboration with the Food Microbiology lab) • Evaluation of cytotoxic and anti-proliferative activity of polyphenols metabolites and other food bioactive compounds against colonic adenocarcinoma cell lines. • Identification of new natural compounds with specific biological activity concerning the modulation of digestive enzyme, the protection against oxidative stress and protein glycation. |
| Address | via Giuseppe Campi, 287 - 41125 Modena |
| Keywords | polyphenols, peptidomic, mass spectrometry, colon cancer, bioactivity |
| ERC Sectors | |
| Instrumentation | Cell culture facilities, spectrofluorimeter, spectrophotometer, electrophoresis and western blot facilities, microplate reader |
| Research Lines | Agrifood and Environment |
| Methodologies | Cell culture techniques (colon cancer cell lines), mass spectrometry, peptidomics, enzymology, protein/peptide purification, western blot, simulated digestion protocols, polyphenol determination in food. |