Laboratorio di ricerca
| Lab. name | PHYTO and MORE |
|---|---|
| Principal Investigator | Stefania Benvenuti |
| Components | Stefania Benvenuti (Principal Investigator
)
Eleonora Truzzi (Assegnista ) |
| Description | Medicinal plants are today still the primary form of health care for the developing countries and also widely used as supplement or substitute to conventional drugs in the developed ones. These products require a pharmaceutical level of assurance for efficacy and safety in their use. Multiple constituents, working “synergistically”, are usually responsible for their therapeutic effects. Consequently, it is necessary to define all the constituents of plant extracts and nutraceuticals to understand the bioactivity and possible adverse effects of active compounds, and to enhance product quality control. High-performance liquid chromatography (HPLC) and gas chromatography (GC), often hyphenated with mass spectrometry (MS), are highly recommended methodologies and widely applied in the ambit of natural product analysis. The expertise of the “PHYTO AND MORE” laboratory is specific for this ambit of research and the studies which have been carried out in recent years were developed thanks to national and international research collaboration. |
| Address | via Giuseppe Campi, 103 - 41125 Modena |
| Keywords | phytochemical analysis, chromatography, extraction, natural products, essential oils |
| ERC Sectors | LS2_4 Metabolomics LS6_11 Prevention and treatment of infection by pathogens (e.g. vaccination, antibiotics, fungicide) LS6_13 Veterinary medicine and infectious diseases in animals LS7_3 Pharmacology, pharmacogenomics, drug discovery and design, drug therapy LS7_8 Health services, health care research LS7_9 Public health and epidemiology |
| Instrumentation | HPLC-UV, HPLC-DAD, HPLC-ESI-MSn (CIGS), HPLC-ESI-MS/MS (CIGS), GC-FID, GC-MS (LADAC), HPTLC |
| Research Lines | Agrifood and Environment |
| Methodologies | Extraction and purification of bioactive compounds from plants; metabolite profiling/fingerprinting of natural products by means of advanced analytical techniques; method development and validation for the extraction and analysis of plant secondary metabolites; evaluation of the biological activity of plant extracts and isolated compounds (in collaboration with other research groups). |